Eight medicines. Six guides. The interaction that actually hurts people sits above the strength.
Doses, warnings and interactions come off the current FDA prescribing information - not marketing copy or forum lore.
The thing that can hurt you goes at the top in plain words. Nitrates, tendons, pregnancy, tapers - no burying the lede.
Every medicine ends with a reader consultation, answered by a named physician who signs their work.
The medicines
Antiparasitics, antibiotics, an acne drug people fear, a steroid, a nerve-pain pill and the erection tablets - each one explained end to end.
Pick the rhythm before you argue about a cash quote. Cialis 10 mg as-needed is a pulse: swallow before anticipated activity, peak near two hours, a us…
Read the facts Antibiotic / fluoroquinoloneCiprofloxacin carries a boxed warning for tendon rupture, nerve damage, and muscle weakness. Those reactions can start within hours to days of a 500 m…
Read the facts Men's health / PDE5 inhibitorHigh-fat pizza plus a 25 mg tablet is a clock problem, not proof the molecule died. Fasting peak sits near one hour. A fat meal can push Tmax about si…
Read the facts CorticosteroidPrednisone 20 mg is a corticosteroid tablet, a synthetic stand-in for cortisol. Yes, it is a steroid, and 20 mg is a relatively high adult strength. E…
Read the facts AntiparasiticHuman ivermectin is Stromectol, a 3 mg tablet for intestinal strongyloidiasis and onchocerciasis (river blindness). The FDA has not authorized it to t…
Read the facts Pain / anticonvulsantGabapentin 300 mg is generic Neurontin. It treats postherpetic neuralgia after shingles and is used as add-on therapy for partial-onset seizures. It i…
Read the facts Men's health / PDE5 inhibitorBrand Levitra left U.S. shelves. Generic <a href="https://en.wikipedia.org/wiki/Vardenafil" rel="noopener" target="_blank">vardenafil</a> stayed. Most…
Read the facts Retinoid / acneIsotretinoin, once sold as Accutane, stays behind iPLEDGE: two negative pregnancy tests before the first fill, then a monthly test and counseling befo…
Read the factsThe guides
Short reads that connect the dots between drugs - how the erection pills fire, why fluoroquinolones carry boxed warnings, what a steroid taper is really for.
Sexual stimulation opens a local chemical tap. Nerves and vessel lining release nitric oxide. That gas tells penile smooth muscle to relax. Blood fill…
Open guide PFB-13Boxed fluoroquinolone text outlived every brand rename. Tendon rupture, lasting neuropathy, and CNS effects sit on the label whether the bottle says C…
Open guide PFB-16Leaving a pharmacologic glucocorticoid needs a plan. Prednisone 20 mg is a common start, not a finish. After about two weeks at that range the adrenal…
Open guide PFB-12Three labeled clocks share one enzyme. This site's featured strengths are sildenafil twenty-five, tadalafil ten, and vardenafil two-point-five. They a…
Open guide PFB-14Federal REMS paperwork decides who swallows isotretinoin. A 20 mg capsule is a real teratogen with a real door. Two contraceptives, monthly pregnancy …
Open guide PFB-15Creatinine clearance owns the first decision. Gabapentin leaves unchanged through the kidney. A 600 mg capsule that ignores CrCl is a sedation plan, n…
Open guideOur doctors
Two physicians split the catalogue by what they know best, and put their names on the answers at the bottom of every page.
Dense prescribing information, turned into pages a real person can finish — with a named doctor answering the questions people actually ask.
Browse the medicines